NANDROLONE DECANOATE INJECTION

NAME OF THE MEDICINAL PRODUCT

Nandrolone DecanoateInjection I.P 25 mg/ml

Brand Name: DecaDuralin 25

Nandrolone Decanoate Injection I.P 50 mg/ml

Brand Name: DecaDuralin50

Nandrolone Decanoate Injection I.P 100mg/ml(1 ml ampoule) 

Brand Name: DecaDuralin 100

Nandrolone Decanoate Injection B.P 200 mg/ml (2 ml Amp. & 5, 10 ml Vial)

Brand Name: DecaDuralin 200

Nandrolone Decanoate Injection B.P 250 mg/ml (10 ml Vial)

Brand Name:DecaDuralin 250)

Nandrolone Description

A sterile oleaginous solution containing per mL: Nandrolone Decanoate 200 mg with Benzyl Alcohol 5% as solubilizer/preservative, in Sesame Oil q.s. Nandrolone decanoate (C28H44O3) occurs as a fine, white to creamy white, crystalline powder. It is odorless, or may have a slight odor.  Nandrolone decanoate is soluble in chloroform, in alcohol, in acetone, and in vegetable oils.  It is practically insoluble in water.

Nandrolone – Clinical Pharmacology

Anabolic steroids are synthetic derivatives of testosterone.  Certain clinical effects and adverse reactions demonstrate the androgenic properties of this class of drugs.  Complete dissociation of anabolic and androgenic effects has not been achieved.  The actions of anabolic steroids are therefore similar to those of male sex hormones with the possibility of causing serious disturbances of growth and sexual development if given to young children.  Anabolic steroids suppress the gonadotropic functions of the pituitary and may exert a direct effect upon the testis.  Anabolic steroids have been reported to increase low-density lipoproteins and decrease high-density lipoproteins.  These changes revert to normal on discontinuation of treatment.

Indications and Usage for Nandrolone

Nandrolone decanoate is indicated for the management of the anemia of renal insufficiency and has been shown to increase hemoglobin and red cell mass. Surgically induced anephric patients have been reported to be less responsive.

Contraindications

  1. Male patients with carcinoma of the breast or with known or suspected carcinoma of the prostate.
  2. Carcinoma of the breast in females with hypercalcemia: androgenic anabolic steroids may stimulate osteolytic resorption of bones.
  3. Pregnancy, because of masculinization of the fetus.
  4. Nephrosis or the nephrotic phase of nephritis.

Adverse Reactions

Hepatic: 
Hepatocellular neoplasms and peliosis hepatis have been reported in association with long-term androgenic anabolic steroid therapy (see WARNINGS section).

Genitourinary System: 
In men.

  1. Prepubertal: Phallic enlargement and increased frequency of erections.
  2. Postpubertal: Inhibition of testicular function, testicular atrophy and oligospermia, impotence, chronic priapism, epididymitis and bladder irritability.

In women: Clitoral enlargement, menstrual irregularities. In both sexes: Increased or decreased libido.

CNS: 
Habituation, excitation, insomnia, depression.

Gastrointestinal: 
Nausea, vomiting, diarrhea.

Hematologic: 
Bleeding in patients on concomitant anticoagulant therapy (see PRECAUTIONS, Drug Interactions).

Breast: 
Gynecomastia.

Larynx: 
Deepening of the voice in women.

Hair: 
Hirsutism and male pattern of baldness in women.

Skin: 
Acne (especially in women and prepubertal boys.)

Skeletal: 
Premature closure of epiphyses in children (see PRECAUTIONS, Pediatric use).

Related Portfolio Items

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut Aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit.